S5E52: Cancer Gone Wild – Learn All About Metastasis

Like the seeds of a dandelion drift on the wind and land other places, cancer can spread under the right conditions. How does cancer spread and why does it happen? We tackle these questions in this episode in our series “Everything you always wanted to know about cancer, but didn’t have anyone to ask.”

In This Episode:

Transcript

  • 3:44 – Road Trip: Missouri and Recipe for Gooey Butter Cake
  • 5:22 – What is Your Life’s Resume? A Short Guide to a Happy Life
  • 8:10 – What Makes Cancer Spread? (Metastasize)
  • 11:33 – Why Does Metastasis Happen?
  • 13:58 – Where Does Cancer Tend to Spread To?
  • 16:02 – Discussion About Metastatic Cancer
  • 17:42 – Discussion – How Do You Find Cancer?
  • 23:26 – What’s Left of Me: Poems of a Dead Soul
  • 24:12 – Outro

What is Metastasis?

Simply put, metastasis is when the cancer moves from the original organ to another part of the body. The goal of treating metastatic cancer is to control it by stopping or slowing its growth. Some people can live for years with metastatic cancer that is well-controlled. The treatment depends on the type of primary cancer, where it has spread, previous cancer treatments, and general health.

Rogue Cancer Cells – Metastasis

Cancer researchers, at the most basic level, focus their energy on what makes cancer cells start in the first place and what makes it metastasize. We’ve been talking the last few weeks about the basic aspects of cancer and this week we are going to talk about cancer cells going rogue and moving through the body. This is called metastasis or stage 4 cancer.

Many cancer deaths are caused when cancer moves from the original tumor and spreads to other tissues and organs. This is called metastatic cancer. This animation shows how cancer cells travel from the place in the body where they first formed to other parts of the body. Many cancer deaths are caused when cancer moves from the original tumor and spreads to other tissues and organs. This is called metastatic cancer. This animation shows how cancer cells travel from the place in the body where they first formed to other parts of the body.

Where Does Cancer Tend to Spread To?

Cancers spread to distant locations based on the type of the original tumor. See the table below for common metastasis locations. Sometimes pain or dysfunction of organs in these locations are the first sign of cancer.

Common Metastasis Sites by Cancer Type

Cancer TypeMain Sites of Metastasis
BladderBone, liver, lung
BreastBone, brain, liver, lung
ColonLiver, lung, peritoneum
KidneyAdrenal gland, bone, brain, liver, lung
LungAdrenal gland, bone, brain, liver, other lung
MelanomaBone, brain, liver, lung, skin, muscle
OvaryLiver, lung, peritoneum
PancreasLiver, lung, peritoneum
ProstateAdrenal gland, bone, liver, lung
RectalLiver, lung, peritoneum
StomachLiver, lung, peritoneum
ThyroidBone, liver, lung
UterusBone, liver, lung, peritoneum, vagina
Source: National Cancer Institute, When Cancer Spreads

Metastatic cancer does not always cause symptoms. When symptoms do occur, what they are like and how often you have them will depend on the size and location of the metastatic tumors. Some common signs of metastatic cancer include:

  • jaundice or swelling in the belly, when cancer has spread to the liver
  • pain and fractures, when cancer has spread to the bone
  • headache, seizures, or dizziness, when cancer has spread to the brain
  • shortness of breath, when cancer has spread to the lung

Related Episodes:

See our other episodes in our series about cancer:

In S5E50: What is Meant by Cancer Staging? Learn the Language of a Cancer Diagnosis, we go in depth into how cancer is staged and what it means.

References:

Resources:

Recipe of the Week: Gooey Butter Cake

This week we travel to Missouri, and St. Louis holds a Gooey Butter cake that will kill your diet but please your sweet tooth! Get the recipe from Chef Billy Parisi.



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